The Nonplanar Secretory IgA2 and Near Planar Secretory IgA1 Solution Structures Rationalize Their Different Mucosal Immune Responses

Secretory IgA (SIgA) is the most prevalent human antibody and is central to mucosal immunity. It exists as two subclasses, SIgA1 and SIgA2, where SIgA2 has a shorter hinge joining the Fab and Fc regions. Both forms of SIgA are predominantly dimeric and contain an additional protein called the secret...

Full description

Saved in:
Bibliographic Details
Main Authors: Bonner, Alexandra, Almogren, Adel, Furtado, Patricia B., Kerr, Michael A., Perkins, Stephen J.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Protein Structure and Folding
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643523/
https://ncbi.nlm.nih.gov/pubmed/19109255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807529200
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items