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The Nonplanar Secretory IgA2 and Near Planar Secretory IgA1 Solution Structures Rationalize Their Different Mucosal Immune Responses

Secretory IgA (SIgA) is the most prevalent human antibody and is central to mucosal immunity. It exists as two subclasses, SIgA1 and SIgA2, where SIgA2 has a shorter hinge joining the Fab and Fc regions. Both forms of SIgA are predominantly dimeric and contain an additional protein called the secret...

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Bibliografiset tiedot
Päätekijät: Bonner, Alexandra, Almogren, Adel, Furtado, Patricia B., Kerr, Michael A., Perkins, Stephen J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643523/
https://ncbi.nlm.nih.gov/pubmed/19109255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807529200
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