Regulation of C-type Lectin Antimicrobial Activity by a Flexible N-terminal Prosegment

Members of the RegIII family of intestinal C-type lectins are directly antibacterial proteins that play a vital role in maintaining host-bacterial homeostasis in the mammalian gut, yet little is known about the mechanisms that regulate their biological activity. Here we show that the antibacterial a...

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Bibliografiske detaljer
Main Authors: Mukherjee, Sohini, Partch, Carrie L., Lehotzky, Rebecca E., Whitham, Cecilia V., Chu, Hiutung, Bevins, Charles L., Gardner, Kevin H., Hooper, Lora V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Protein Synthesis, Post-Translational Modification, and Degradation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643518/
https://ncbi.nlm.nih.gov/pubmed/19095652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808077200
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