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Purinergic P2X(7) Receptors Mediate ATP-induced Saliva Secretion by the Mouse Submandibular Gland

Salivary glands express multiple isoforms of P2X and P2Y nucleotide receptors, but their in vivo physiological roles are unclear. P2 receptor agonists induced salivation in an ex vivo submandibular gland preparation. The nucleotide selectivity sequence of the secretion response was BzATP ≫ ATP >...

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Detalhes bibliográficos
Main Authors: Nakamoto, Tetsuji, Brown, David A., Catalán, Marcelo A., Gonzalez-Begne, Mireya, Romanenko, Victor G., Melvin, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643514/
https://ncbi.nlm.nih.gov/pubmed/19097994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808597200
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