Effective Treatment of Established Human Breast Tumor Xenografts in Immunodeficient Mice with a Single Dose of the α-Emitting Radioisotope Astatine-211 Conjugated to Anti-HER2/neu Diabodies

Successful RAIT strategies depend upon selecting radioisotopes with physical properties complementary to the biological properties of the targeting vehicle. Small, engineered anti-tumor antibody fragments are capable of rapid, highly specific tumor targeting in immunodeficient mouse models. We hypot...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Robinson, Matthew K., Shaller, Calvin, Garmestani, Kayhan, Plascjak, Paul S., Hodge, Kathryn M., Yuan, Qing-An, Marks, James D., Waldmann, Thomas A., Brechbiel, Martin W., Adams, Gregory P.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2008
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643368/
https://ncbi.nlm.nih.gov/pubmed/18245551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-1250
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