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Absence epilepsy in apathetic, a spontaneous mutant mouse lacking the h channel subunit, HCN2

Analysis of naturally occurring mutations that cause seizures in rodents has advanced understanding of the molecular mechanisms underlying epilepsy. Abnormalities of I(h) and h channel expression have been found in many animal models of absence epilepsy. We characterized a novel spontaneous mutant m...

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Detalhes bibliográficos
Main Authors: Chung, Wendy K., Shin, Minyoung, Jaramillo, Thomas C., Leibel, Rudolph L., LeDuc, Charles A., Fischer, Stuart G., Tzilianos, Efthia, Gheith, Ayman A., Lewis, Alan S., Chetkovich, Dane M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643333/
https://ncbi.nlm.nih.gov/pubmed/19150498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2008.12.004
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