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Leukocyte-Derived IL-10 Reduces Subepithelial Fibrosis Associated with Chronically Inhaled Endotoxin

Endotoxin (LPS), a Gram-negative cell wall component, has potent proinflammatory properties. Acute LPS exposure causes airway inflammation; chronic exposure causes airway hyperreactivity and remodeling. IL-10 is an important antiinflammatory cytokine, which is decreased in patients with airway disea...

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Hlavní autoři: Garantziotis, Stavros, Brass, David M., Savov, Jordan, Hollingsworth, John W., McElvania-TeKippe, Erin, Berman, Katie, Walker, Julia K. L., Schwartz, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643294/
https://ncbi.nlm.nih.gov/pubmed/16809636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2006-0055OC
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