Immortalization of Human Alveolar Epithelial Cells to Investigate Nanoparticle Uptake

Primary human alveolar type 2 (AT2) cells were immortalized by transduction with the catalytic subunit of telomerase and simian virus 40 large-tumor antigen. Characterization by immunochemical and morphologic methods demonstrated an AT1-like cell phenotype. Unlike primary AT2 cells, immortalized cel...

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Hlavní autoři: Kemp, Sarah J., Thorley, Andrew J., Gorelik, Julia, Seckl, Michael J., O'Hare, Michael J., Arcaro, Alexandre, Korchev, Yuri, Goldstraw, Peter, Tetley, Teresa D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643209/
https://ncbi.nlm.nih.gov/pubmed/18539954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2007-0334OC
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