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Vinflunine in the treatment of bladder cancer

Vinflunine (VFL) is a third-generation bifluorinated semi-synthetic vinca alkaloid obtained by superacidic chemistry from its parent compound, vinorelbine. As with the other vinca alkaloids, the main antineoplastic effects of VFL arise from its interaction with tubulin, the major component of microt...

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Autors principals: Bachner, Mark, De Santis, Maria
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643105/
https://ncbi.nlm.nih.gov/pubmed/19337431
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