Genetic risk factors for variant Creutzfeldt–Jakob disease: a genome-wide association study

BACKGROUND: Human and animal prion diseases are under genetic control, but apart from PRNP (the gene that encodes the prion protein), we understand little about human susceptibility to bovine spongiform encephalopathy (BSE) prions, the causal agent of variant Creutzfeldt–Jakob disease (vCJD). METHOD...

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Detalhes bibliográficos
Main Authors: Mead, Simon, Poulter, Mark, Uphill, James, Beck, John, Whitfield, Jerome, Webb, Thomas EF, Campbell, Tracy, Adamson, Gary, Deriziotis, Pelagia, Tabrizi, Sarah J, Hummerich, Holger, Verzilli, Claudio, Alpers, Michael P, Whittaker, John C, Collinge, John
Formato: Artigo
Idioma:Inglês
Publicado em: Lancet Pub. Group 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643048/
https://ncbi.nlm.nih.gov/pubmed/19081515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(08)70265-5
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