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Activation of human complement by the pneumococcal toxin pneumolysin.

Highly purified pneumolysin (at a concentration of 10 micrograms/ml) caused significant activation of human complement, as measured by conversion of C3. Complement activation in the presence of pneumolysin was not observed in sera chelated with a combination of Mg2+ and ethylene glycol-bis(beta-amin...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Paton, J C, Rowan-Kelly, B, Ferrante, A
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1984
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC264298/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6698602/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.43.3.1085-1087.1984
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