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REDUCTION OF L-METHIONINE SELENOXIDE TO SELENO-L-METHIONINE BY ENDOGENOUS THIOLS, ASCORBIC ACID, OR METHIMAZOLE

Seleno-L-methionine (SeMet) can be oxidized to L-methionine selenoxide (MetSeO) by flavin-containing monooxygenase 3 (FMO3) and rat liver microsomes in the presence of NADPH. MetSeO can be reduced by GSH to yield SeMet and GSSG. In the present study, the potential reduction of MetSeO to SeMet by oth...

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Autori principali: Krause, Renee J., Elfarra, Adnan A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642925/
https://ncbi.nlm.nih.gov/pubmed/18930712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.09.022
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