Toxoids of Pseudomonas aeruginosa exotoxin-A: photoaffinity inactivation of purified toxin and purified toxin derivatives.

For the preparation of greatly detoxified but highly immunogenic toxoids, two enzymatically active, low-toxicity derivatives of Pseudomonas aeruginosa exotoxin-A were further inactivated by photoaffinity labeling. These derivatives were formed during toxin purification, when a relatively crude toxin...

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Bibliographic Details

Published in:	Infect Immun
Main Authors:	Callahan, L T, Martinez, D, Marburg, S, Tolman, R L, Galloway, D R
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1984
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC264287/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6321348/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.43.3.1019-1026.1984
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