Activity of mevalonate pathway inhibitors against breast and ovarian cancers in the ATP-based tumour chemosensitivity assay

Previous data suggest that lipophilic statins such as fluvastatin and N-bisphosphonates such as zoledronic acid, both inhibitors of the mevalonate metabolic pathway, have anti-cancer effects in vitro and in patients. We have examined the effect of fluvastatin alone and in combination with zoledronic...

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Detalhes bibliográficos
Main Authors: Knight, Louise A, Kurbacher, Christian M, Glaysher, Sharon, Fernando, Augusta, Reichelt, Ralf, Dexel, Susanne, Reinhold, Uwe, Cree, Ian A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642836/
https://ncbi.nlm.nih.gov/pubmed/19175937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-38
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