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Issues associated with assessing nuclear localization of N-terminally unphosphorylated β-catenin with monoclonal antibody 8E7

BACKGROUND: β-catenin is a dual function adhesion/transcriptional co-activator protein, and both functions are critical for normal tissue homeostasis. Since the transcriptional functions of β-catenin are more often implicated in various disease processes, there is much interest in the development an...

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Detalhes bibliográficos
Main Authors: Maher, Meghan T, Flozak, Annette S, Hartsell, Alyssa M, Russell, Susan, Beri, Rohinee, Peled, Ofra N, Gottardi, Cara J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642777/
https://ncbi.nlm.nih.gov/pubmed/19187541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-4-5
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