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Role of SP transcription factors in hormone-dependent modulation of genes in MCF-7 breast cancer cells: microarray and RNA interference studies

17β-Estradiol (E(2)) binds estrogen receptor α (ESR1) in MCF-7 cells and increases cell proliferation and survival through induction or repression of multiple genes. ESR1 interactions with DNA-bound specificity protein (SP) transcription factors is a nonclassical genomic estrogenic pathway and the r...

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Main Authors: Wu, Fei, Ivanov, Ivan, Xu, Rui, Safe, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642616/
https://ncbi.nlm.nih.gov/pubmed/18952783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JME-08-0088
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