Subepidermal Blistering Induced by Human Autoantibodies to BP180 Requires Innate Immune Players in a Humanized Bullous Pemphigoid Mouse Model

Bullous pemphigoid (BP) is a cutaneous autoimmune inflammatory disease associated with subepidermal blistering and autoantibodies against BP180, a transmembrane collagen and major component of the hemidesmosome. Numerous inflammatory cells infiltrate the upper dermis in BP. IgG autoantibodies in BP...

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Main Authors: Liu, Zhi, Sui, Wen, Zhao, Minglang, Li, Zhuowei, Li, Ning, Thresher, Randy, Giudice, George J., Fairley, Janet A., Sitaru, Cassian, Zillikens, Detlef, Ning, Gang, Marinkovich, Peter, Diaz, Luis A.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642586/
https://ncbi.nlm.nih.gov/pubmed/18922680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2008.08.00
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