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The Aurora kinase A Regulates GSK-3β in Gastric Cancer Cells

Aurora kinase A (AURKA) is located at 20q13, a region that is frequently amplified in gastric cancer. In this study, we have investigated the role of AURKA in regulating GSK-3β and β-catenin/TCF complex in gastric cancer cells. Our results demonstrate a significant increase in the phosphorylation of...

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Main Authors: Dar, Altaf A, Belkhiri, Abbes, El-Rifai, Wael
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2642527/
https://ncbi.nlm.nih.gov/pubmed/19060929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.434
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