Cell-Autonomous Requirement for Rx Function in the Mammalian Retina and Posterior Pituitary

Rx is a paired-like homeobox gene that is required for vertebrate eye formation. Mice lacking Rx function do not develop eyes or the posterior pituitary. To determine whether Rx is required cell autonomously in these tissues, we generated embryonic chimeras consisting of wild type and Rx−/− cells. W...

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Detalhes bibliográficos
Main Authors: Medina-Martinez, Olga, Amaya-Manzanares, Felipe, Liu, Chaomei, Mendoza, Marisela, Shah, Rina, Zhang, Li, Behringer, Richard R., Mahon, Kathleen A., Jamrich, Milan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2641000/
https://ncbi.nlm.nih.gov/pubmed/19229337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004513
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