Migfilin, a Molecular Switch in Regulation of Integrin Activation

The linkage of heterodimeric (α/β) integrin receptors with their extracellular matrix ligands and intracellular actin cytoskeleton is a fundamental step for controlling cell adhesion and migration. Binding of the actin-linking protein, talin, to integrin β cytoplasmic tails (CTs) induces high affini...

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Bibliografiska uppgifter
Huvudupphovsmän: Ithychanda, Sujay Subbayya, Das, Mitali, Ma, Yan-Qing, Ding, Keyang, Wang, Xiaoxia, Gupta, Sudhiranjan, Wu, Chuanyue, Plow, Edward F., Qin, Jun
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2009
Ämnen:
Mechanisms of Signal Transduction
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640964/
https://ncbi.nlm.nih.gov/pubmed/19074766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807719200
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