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Mutators and long-term molecular evolution of pathogenic Escherichia coli O157:H7.

It has been proposed that an increased mutation rate (indicated by the frequency of hypermutable isolates) has facilitated the emergence of Escherichia coli O157:H7. Analysis of the divergence of 12 genes shows no evidence that the pathogen has undergone an unusually high rate of mutation and molecu...

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Autors principals: Whittam, T S, Reid, S D, Selander, R K
Format: Artigo
Idioma:Inglês
Publicat: Centers for Disease Control and Prevention 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640239/
https://ncbi.nlm.nih.gov/pubmed/9866737
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