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Medial orbitofrontal cortex gray matter is reduced in abstinent substance dependent individuals

BACKGROUND: Chronic exposure to drugs of addiction induces cellular adaptations in orbitofrontal cortex (OFC) and associated limbic-prefrontal pathways that may underlie abuse-related behavior. A propensity to make risky decisions in spite of substantial negative consequences may be mediated by medi...

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Detalhes bibliográficos
Main Authors: Tanabe, Jody, Tregellas, Jason R., Thompson, Laetitia, Dalwani, Manish, Owens, Elizabeth, Crowley, Thomas, Banich, Marie
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640220/
https://ncbi.nlm.nih.gov/pubmed/18801475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2008.07.030
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