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Altered sterol profile induced in Leishmania amazonensis by a natural dihydroxymethoxylated chalcone

OBJECTIVES: The effects of the antileishmanial chalcone 2′,6′-dihydroxy-4′-methoxychalcone (DMC) on Leishmania amazonensis sterol composition and biosynthesis were investigated to obtain information about the mechanism of growth inhibition by DMC on this parasite. METHODS: The interference of sterol...

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Detalhes bibliográficos
Main Authors: Torres-Santos, Eduardo Caio, Sampaio-Santos, Maria Isabel, Buckner, Frederick S., Yokoyama, Kohei, Gelb, Michael, Urbina, Julio A., Rossi-Bergmann, Bartira
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640159/
https://ncbi.nlm.nih.gov/pubmed/19176591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkn546
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