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Transduction of PACAP38 protects primary cortical neurons from neurotoxic injury

Neurotrophic factors such as pituitary adenylate cyclase activating polypeptide (PACAP38) are promising therapeutics for neurodegenerative diseases. However, delivery of trophic factors into brain neurons remains a challenge. The objective of this study is to determine whether adeno-associated virus...

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Bibliographic Details
Main Authors: Sanchez, Alma, Chiriva-Internati, Maurizo, Grammas, Paula
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640109/
https://ncbi.nlm.nih.gov/pubmed/18938212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2008.10.021
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