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Pimecrolimus Enhances TLR2/6-Induced Expression of Antimicrobial Peptides in Keratinocytes

Calcineurin inhibitors are potent inhibitors of T-cell-receptor mediated activation of the adaptive immune system. The effects of this class of drug on the innate immune response system are not known. Keratinocytes are essential to innate immunity in skin and rely on toll-like receptors (TLRs) and a...

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Autori principali: Büchau, Amanda S., Schauber, Jürgen, Hultsch, Thomas, Stuetz, Anton, Gallo, Richard L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639780/
https://ncbi.nlm.nih.gov/pubmed/18496569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2008.135
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