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Identification of Amino Acids Important for the Biochemical Activity of Methanothermobacter thermautotrophicus MCM

Methanothermobacter thermautotrophicus minichromosomal maintenance protein (mtMCM) is a 75 kDa protein that self-assembles into a double hexamer structure. The double hexamer formed by the N-terminal region of mtMCM has a highly charged (overwhelmingly net positive) inner channel. Here we investigat...

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Detalhes bibliográficos
Main Authors: Fletcher, Ryan J., Shen, Jingping, Holden, Lauren G., Chen, Xiaojiang S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639774/
https://ncbi.nlm.nih.gov/pubmed/18754676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800032t
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