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Fatness-Associated FTO Gene Variant Increases Mortality Independent of Fatness – in Cohorts of Danish Men

BACKGROUND: The A-allele of the single nucleotide polymorphism (SNP), rs9939609, in the FTO gene is associated with increased fatness. We hypothesized that the SNP is associated with morbidity and mortality through the effect on fatness. METHODOLOGY/PRINCIPAL FINDINGS: In a population of 362,200 Dan...

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Hlavní autoři: Zimmermann, Esther, Kring, Sofia I. I., Berentzen, Tina L., Holst, Claus, Pers, Tune H., Hansen, Torben, Pedersen, Oluf, Sørensen, Thorkild I. A., Jess, Tine
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639637/
https://ncbi.nlm.nih.gov/pubmed/19214238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004428
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