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Fatness-Associated FTO Gene Variant Increases Mortality Independent of Fatness – in Cohorts of Danish Men

BACKGROUND: The A-allele of the single nucleotide polymorphism (SNP), rs9939609, in the FTO gene is associated with increased fatness. We hypothesized that the SNP is associated with morbidity and mortality through the effect on fatness. METHODOLOGY/PRINCIPAL FINDINGS: In a population of 362,200 Dan...

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Detalhes bibliográficos
Main Authors: Zimmermann, Esther, Kring, Sofia I. I., Berentzen, Tina L., Holst, Claus, Pers, Tune H., Hansen, Torben, Pedersen, Oluf, Sørensen, Thorkild I. A., Jess, Tine
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639637/
https://ncbi.nlm.nih.gov/pubmed/19214238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004428
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