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Mechanisms of Withdrawal-Associated Increases in Heroin Self-Administration: Pharmacologic Modulation of Heroin vs. Food Choice in Heroin-Dependent Rhesus Monkeys

Opioid withdrawal can produce a constellation of physiological and behavioral signs, including an increase in opioid self-administration. Different mechanisms mediate different withdrawal signs, and the present study used pharmacologic tools to assess mechanisms underlying withdrawal-associated incr...

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Detalhes bibliográficos
Main Authors: Negus, S. Stevens, Rice, Kenner C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639629/
https://ncbi.nlm.nih.gov/pubmed/18704098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2008.127
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