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An HPV 16 L1-based chimeric human papilloma virus-like particles containing a string of epitopes produced in plants is able to elicit humoral and cytotoxic T-cell activity in mice

BACKGROUND: Even though two prophylactic vaccines against HPV are currently licensed, infections by the virus continue to be a major health problem mainly in developing countries. The cost of the vaccines limits wide-scale application in poor countries. A promising strategy for producing affordable...

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Autori principali: De la Rosa, Georgina Paz, Monroy-García, Alberto, Mora-García, María de Lourdes, Peña, Cristina Gehibie Reynaga, Hernández-Montes, Jorge, Weiss-Steider, Benny, Lim, Miguel Angel Gómez
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639544/
https://ncbi.nlm.nih.gov/pubmed/19126233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-6-2
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