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Microsomal omega-hydroxylated metabolites of N-arachidonoyl dopamine are active at recombinant human TRPV(1) receptors

N-arachidonoyl dopamine (NADA) is an endogenous lipid that modulates signal transduction in neuronal and immune pathways. NADA activates the non-selective cation channel, transient receptor potential vanilloid type 1 (TRPV(1)) and cannabinoid receptor 1. That NADA is comprised of an arachidonic acid...

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Detalhes bibliográficos
Main Authors: Rimmerman, N, Bradshaw, H.B, Basnet, A, Tan, B, Widlanski, Theodore S, Walker, J.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639396/
https://ncbi.nlm.nih.gov/pubmed/18812233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2008.08.004
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