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Position-dependent motif characterization using non-negative matrix factorization
Motivation: Cis-acting regulatory elements are frequently constrained by both sequence content and positioning relative to a functional site, such as a splice or polyadenylation site. We describe an approach to regulatory motif analysis based on non-negative matrix factorization (NMF). Whereas exist...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2639279/ https://ncbi.nlm.nih.gov/pubmed/18852176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btn526 |
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