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Polymorphisms in estrogen- and androgen-metabolizing genes and the risk of gastric cancer

Androgens and estrogens may play a role in gastric cancer etiology. To investigate the association of gastric cancer with single-nucleotide polymorphisms (SNPs) in six genes (COMT, CYP1B1, CYP17A1, CYP19A1, HSD17B1 and SHBG) involved in estrogen and androgen synthesis and metabolism, 58 haplotype-ta...

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Detalhes bibliográficos
Main Authors: Freedman, Neal D., Ahn, Jiyoung, Hou, Lifang, Lissowska, Jolanta, Zatonski, Witold, Yeager, Meredith, Chanock, Stephen J., Chow, Wong Ho, Abnet, Christian C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639034/
https://ncbi.nlm.nih.gov/pubmed/19015200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn258
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