The Cortical Signature of Alzheimer's Disease: Regionally Specific Cortical Thinning Relates to Symptom Severity in Very Mild to Mild AD Dementia and is Detectable in Asymptomatic Amyloid-Positive Individuals

Alzheimer's disease (AD) is associated with neurodegeneration in vulnerable limbic and heteromodal regions of the cerebral cortex, detectable in vivo using magnetic resonance imaging. It is not clear whether abnormalities of cortical anatomy in AD can be reliably measured across different subje...

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Detalhes bibliográficos
Main Authors: Dickerson, Bradford C., Bakkour, Akram, Salat, David H., Feczko, Eric, Pacheco, Jenni, Greve, Douglas N., Grodstein, Fran, Wright, Christopher I., Blacker, Deborah, Rosas, H. Diana, Sperling, Reisa A., Atri, Alireza, Growdon, John H., Hyman, Bradley T., Morris, John C., Fischl, Bruce, Buckner, Randy L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Feature Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638813/
https://ncbi.nlm.nih.gov/pubmed/18632739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhn113
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