Id-1 as a molecular target in therapy for breast cancer cell invasion and metastasis

Mammary epithelial cells constitutively expressing Id-1 protein are unable to differentiate, acquire the ability to proliferate, and invade the extracellular matrix. In addition, Id-1 is aberrantly over-expressed in aggressive and metastatic breast cancer cells, as well as in human breast tumor biop...

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Main Authors: Fong, Sylvia, Itahana, Yoko, Sumida, Tomoki, Singh, Jarnail, Coppe, Jean-Philippe, Liu, Yong, Richards, Peter C., Bennington, James L., Lee, Nancy M., Debs, Robert J., Desprez, Pierre-Yves
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2003
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC263850/
https://ncbi.nlm.nih.gov/pubmed/14578451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2230238100
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