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Homocysteine induces congenital defects of the heart and neural tube: Effect of folic acid

The biological basis or mechanism whereby folate supplementation protects against heart and neural tube defects is unknown. It has been hypothesized that the amino acid homocysteine may be the teratogenic agent, since serum homocysteine increases in folate depletion; however, this hypothesis has not...

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Detalhes bibliográficos
Main Authors: Rosenquist, Thomas H., Ratashak, S. Anne, Selhub, Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26385/
https://ncbi.nlm.nih.gov/pubmed/8986792
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