Vaccinia virus-specific CD8(+) T cell responses target a group of epitopes without a strong immunodominance hierarchy in humans

Immunization with vaccinia virus (VACV) resulted in long-lasting protection against smallpox and successful global eradication of the disease. VACV elicits strong cellular as well as humoral immune responses. Although neutralizing antibody is essential for protection, cellular immunity seems to be m...

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Detalhes bibliográficos
Main Authors: Terajima, Masanori, Orphin, Laura, Leporati, Anita M., Pazoles, Pamela, Cruz, John, Rothman, Alan L., Ennis, Francis A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638498/
https://ncbi.nlm.nih.gov/pubmed/18955096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2008.09.009
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