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Cytochrome P450 1B1 Val432Leu polymorphism and breast cancer risk in Nigerian women: a case control study

BACKGROUND: Cytochrome P450 1B1 (CYP1B1) is active in the metabolism of estrogens to reactive catechols and of different procarcinogens. Several studies have investigated the relationship between genetic polymorphisms of CYP1B1 and breast cancer risk with inconsistent results. A G → C transversion p...

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Autori principali: Okobia, Michael N, Bunker, Clareann H, Garte, Seymour J, Zmuda, Joseph M, Ezeome, Emmanuel R, Anyanwu, Stanley NC, Uche, Emmanuel EO, Osime, Usifo, Ojukwu, Joseph, Kuller, Lewis H, Ferrell, Robert E, Taioli, Emanuela
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638457/
https://ncbi.nlm.nih.gov/pubmed/19208203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-9378-4-S1-S12
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