Murine cytomegalovirus m157 mutation and variation leads to immune evasion of natural killer cells

Effective natural killer (NK) cell recognition of murine cytomegalovirus (MCMV)-infected cells depends on binding of the Ly49H NK cell activation receptor to the m157 viral glycoprotein. Here we addressed the immunological consequences of variation in m157 sequence and function. We found that most s...

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Detalhes bibliográficos
Main Authors: Voigt, Valentina, Forbes, Catherine A., Tonkin, Joanne N., Degli-Esposti, Mariapia A., Smith, Hamish R. C., Yokoyama, Wayne M., Scalzo, Anthony A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC263840/
https://ncbi.nlm.nih.gov/pubmed/14597723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2233572100
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