Murine cytomegalovirus m157 mutation and variation leads to immune evasion of natural killer cells

Effective natural killer (NK) cell recognition of murine cytomegalovirus (MCMV)-infected cells depends on binding of the Ly49H NK cell activation receptor to the m157 viral glycoprotein. Here we addressed the immunological consequences of variation in m157 sequence and function. We found that most s...

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Bibliografiske detaljer
Main Authors: Voigt, Valentina, Forbes, Catherine A., Tonkin, Joanne N., Degli-Esposti, Mariapia A., Smith, Hamish R. C., Yokoyama, Wayne M., Scalzo, Anthony A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC263840/
https://ncbi.nlm.nih.gov/pubmed/14597723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2233572100
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