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Endogenous neosynthesis vs. cross-presentation of viral antigens for cytotoxic T cell priming

Induction of antiviral cytotoxic T lymphocytes (CTLs) has been proposed to require cross-presentation of viral antigens derived from infected extralymphatic host cells by antigen-presenting cells (APC). This postulated mechanism of cross-priming is thought to be essential for CTL responses against v...

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Bibliografiske detaljer
Main Authors: Freigang, Stefan, Egger, Denise, Bienz, Kurt, Hengartner, Hans, Zinkernagel, Rolf M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC263839/
https://ncbi.nlm.nih.gov/pubmed/14595029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1835685100
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