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EM-random forest and new measures of variable importance for multi-locus quantitative trait linkage analysis

Motivation: We developed an EM-random forest (EMRF) for Haseman–Elston quantitative trait linkage analysis that accounts for marker ambiguity and weighs each sib-pair according to the posterior identical by descent (IBD) distribution. The usual random forest (RF) variable importance (VI) index used...

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Autori principali: Lee, Sophia S. F., Sun, Lei, Kustra, Rafal, Bull, Shelley B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638262/
https://ncbi.nlm.nih.gov/pubmed/18499695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btn239
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