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Protein kinase C activation stabilizes LDL receptor mRNA via the JNK pathway in HepG2 cells
LDL is the most abundant cholesterol transport vehicle in plasma and a major prognostic indicator of atherosclerosis. Hepatic LDL receptors limit circulating LDL levels, since cholesterol internalized by the liver can be excreted. As such, mechanisms regulating LDL receptor expression in liver cells...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2638102/ https://ncbi.nlm.nih.gov/pubmed/18936517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800316-JLR200 |
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