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EPR Evidence of Cyanide Binding to the Mn(Mg) Center of Cytochrome c Oxidase: Support for Cu(A)–Mg Involvement in Proton Pumping

We examined the anion binding behavior of the Mg(Mn) site in cytochrome c oxidase to test a possible role of this center in proton pumping. Rhodobacter sphaeroides grown in a Mn(II)-rich medium replaces the intrinsic Mg(II) ion with an EPR-detectable Mn(II) ion without change in activity. Due to its...

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Detalhes bibliográficos
Principais autores: Sharpe, Martyn A., Krzyaniak, Matthew D., Xu, Shujuan, McCracken, John, Ferguson-Miller, Shelagh
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638054/
https://ncbi.nlm.nih.gov/pubmed/19108635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801391r
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