Impaired Replication Stress Response in Cells from Immunodeficiency Patients Carrying Cernunnos/XLF Mutations

Non-Homologous End Joining (NHEJ) is one of the two major pathways of DNA Double Strand Breaks (DSBs) repair. Mutations in human NHEJ genes can lead to immunodeficiency due to its role in V(D)J recombination in the immune system. In addition, most patients carrying mutations in NHEJ genes display de...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Schwartz, Michal, Oren, Yifat S., Bester, Assaf C., Rahat, Ayelet, Sfez, Ruthy, Yitzchaik, Shlomo, de Villartay, Jean-Pierre, Kerem, Batsheva
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637976/
https://ncbi.nlm.nih.gov/pubmed/19223975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004516
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados