Visualizing breathing motion of internal cavities in concert with ligand migration in myoglobin

Proteins harbor a number of cavities of relatively small volume. Although these packing defects are associated with the thermodynamic instability of the proteins, the cavities also play specific roles in controlling protein functions, e.g., ligand migration and binding. This issue has been extensive...

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Main Authors: Tomita, Ayana, Sato, Tokushi, Ichiyanagi, Kouhei, Nozawa, Shunsuke, Ichikawa, Hirohiko, Chollet, Matthieu, Kawai, Fumihiro, Park, Sam-Yong, Tsuduki, Takayuki, Yamato, Takahisa, Koshihara, Shin-ya, Adachi, Shin-ichi
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637904/
https://ncbi.nlm.nih.gov/pubmed/19204297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807774106
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