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Increased PADI4 expression in blood and tissues of patients with malignant tumors
BACKGROUND: Peptidylarginine deiminase type 4 (PAD4/PADI4) post-translationally converts peptidylarginine to citrulline. Recent studies suggest that PADI4 represses expression of p53-regulated genes via citrullination of histones at gene promoters. METHODS: Expression of PADI4 was investigated in va...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2637889/ https://ncbi.nlm.nih.gov/pubmed/19183436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-40 |
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