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Effect of false positive and false negative rates on inference of binding target conservation across different conditions and species from ChIP-chip data

BACKGROUND: ChIP-chip data are routinely used to identify transcription factor binding targets. However, the presence of false positives and false negatives in ChIP-chip data complicates and hinders analyses, especially when the binding targets for a specific transcription factor are compared across...

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Detalhes bibliográficos
Main Authors: Datta, Debayan, Zhao, Hongyu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637844/
https://ncbi.nlm.nih.gov/pubmed/19152696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-23
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