Cellular Expression, Trafficking, and Function of Two Isoforms of Human ULBP5/RAET1G

BACKGROUND: The activating immunoreceptor NKG2D is expressed on Natural Killer (NK) cells and subsets of T cells. NKG2D contributes to anti-tumour and anti-viral immune responses in vitro and in vivo. The ligands for NKG2D in humans are diverse proteins of the MIC and ULBP/RAET families that are upr...

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Main Authors: Eagle, Robert A., Flack, Gillian, Warford, Anthony, Martínez-Borra, Jesús, Jafferji, Insiya, Traherne, James A., Ohashi, Maki, Boyle, Louise H., Barrow, Alexander D., Caillat-Zucman, Sophie, Young, Neil T., Trowsdale, John
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637608/
https://ncbi.nlm.nih.gov/pubmed/19223974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004503
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