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Characterization of 5′ untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences

The human voltage-gated sodium channel gene cluster on chromosome 2q24 contains three paralogs, SCN1A, SCN2A, and SCN3A, which are expressed in the central nervous system. Mutations in SCN1A and SCN2A cause several subtypes of idiopathic epilepsy. Furthermore, many SCN1A mutations are predicted to r...

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Main Authors: Martin, Melinda S., Tang, Bin, Ta, Nga, Escayg, Andrew
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637551/
https://ncbi.nlm.nih.gov/pubmed/17544618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2007.04.006
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