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Genome-wide innate immune responses in HIV-1 infected macrophages are preserved despite attenuation of the NF-κB activation pathway

Macrophages contribute to HIV-1 infection at many levels. They provide permissive cells at the site of inoculation, augment virus transfer to T cells, generate long-lived viral reservoirs and cause bystander cell apoptosis. A body of evidence suggests that the role of macrophages in cellular host de...

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Detalhes bibliográficos
Main Authors: Noursadeghi, Mahdad, Tsang, Jhen, Miller, Robert F., Straschewski, Sarah, Kellam, Paul, Chain, Benjamin M., Katz, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637478/
https://ncbi.nlm.nih.gov/pubmed/19109163
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