The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

A newly identified severe acute respiratory syndrome coronavirus (SARS-CoV), is the etiological agent responsible for the outbreak of SARS. The SARS-CoV main protease, which is a 33.8-kDa protease (also called the 3C-like protease), plays a pivotal role in mediating viral replication and transcripti...

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Autors principals: Yang, Haitao, Yang, Maojun, Ding, Yi, Liu, Yiwei, Lou, Zhiyong, Zhou, Zhe, Sun, Lei, Mo, Lijuan, Ye, Sheng, Pang, Hai, Gao, George F., Anand, Kanchan, Bartlam, Mark, Hilgenfeld, Rolf, Rao, Zihe
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC263746/
https://ncbi.nlm.nih.gov/pubmed/14585926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1835675100
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