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Detection of neuronal loss using T(1ρ) MRI assessment of (1)H(2)O spin dynamics in the aphakia mouse

The loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc) is well characterized in Parkinson’s disease (PD). Recent developments in magnetic resonance imaging (MRI) techniques have provided the opportunity to evaluate for changes in cellular density. Longitudinal relaxation m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Michaeli, Shalom, Burns, Terry C., Kudishevich, Elina, Hanson, Tim, Sorce, Dennis J., Garwood, Michael, Low, Walter C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637389/
https://ncbi.nlm.nih.gov/pubmed/19027791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2008.10.025
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